Peng chen group Peng chen group

RESEARCH

Research direction


We work at the interface of chemistry and biology. Centered around leveraging the live-cell chemistry for mechanistic discovery and therapeutic innovations, we have developed bioorthogonal reactions and chemical probes to understand protein functions and cell communications in health and disease. We employ this toolkit to study how the spatial-temporally organized human proteome is rewired in cancer as well as during immune response, and we also exploit the therapeutic potential of these new discoveries. Research areas in the group include:

1. Bioorthogonal Cleavage Reactions

2. Bioorthogonal Proteomics

3. Bioorthogonal Therapeutics

4. Immuno-Chemical Biology


Research areas


Bioorthogonal Cleavage Reactions in Health and Disease Bioorthogonal Proteomics in Space and Time Bioorthogonal Therapeutics Immuno-Chemical Biology
Zum Anfang